Khan IH. Lithium and non-steroidal anti-inflammatory drugs. BMJ. Naproxen is used to treat pain or inflammation caused by conditions such as arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps. Rest. Rest and protect an injured or sore area. Stop, change, or take a break from any activity that may be causing your pain or soreness. THE RECOMMENDED DOSE IS 250 MG, 375 MG, OR 500 MG TWICE DAILY. DURING LONG-TERM ADMINISTRATION, THE DOSE OF NAPROXEN MAY BE ADJUSTED UP OR DOWN DEPENDING ON THE CLINICAL RESPONSE OF THE PATIENT. A LOWER DAILY DOSE MAY SUFFICE FOR LONG-TERM ADMINISTRATION. THE MORNING AND EVENING DOSES DO NOT HAVE TO BE EQUAL IN SIZE AND THE ADMINISTRATION OF THE DRUG MORE FREQUENTLY THAN TWICE DAILY IS NOT NECESSARY.
Safety and effectiveness in pediatric patients have not been established. Do not bandage or wrap the affected area unless directed otherwise by your doctor. Smith, M. L. Inhibition of human pathogenic fungi by ethnobotanically selected plant extracts. Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.
Vutyavanich T, Kraisarin T, Ruangsri R. Ginger for nausea and vomiting in pregnancy: randomized, double-masked, placebo-controlled trial. NPR LE 500 on one side and scored on the other. Packaged in light-resistant bottles of 100. Individual hives typically fade within 30 minutes to two hours. However, they usually come back when skin is exposed to sun again.
Diabetes. There is inconsistent evidence about the effects of ginger on blood sugar control in people with diabetes. Some research suggests that taking ginger daily in two divided doses for 8 weeks reduces insulin levels, but not blood sugar. Another study shows that ginger affects blood sugar, but not insulin levels. Although it's not clear, the conflicting results may be due to the dose of ginger used or the length of time the patients had been diagnosed with diabetes. For dizziness vertigo: 1 gram of ginger powder as a single dose one hour before causing dizziness has been used. Di, Marzo, V, and Banni, S. Endocannabinoids may mediate the ability of n-3 fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats.
Marfan syndrome, Sjogren's syndrome, or lupus. EC-Naprosyn naproxen delayed-release tablets is available as enteric-coated white tablets containing 375 mg of naproxen and 500 mg of naproxen for oral administration. The inactive ingredients are croscarmellose sodium, povidone and magnesium stearate. The enteric coating dispersion contains methacrylic acid copolymer, talc, triethyl citrate, sodium hydroxide and purified water. If you have other symptoms along with your minor chest pain, see the Related Information section for topics that relate to your other symptoms. Naprosyn may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Naprosyn with caution. Get emergency medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance. NSAIDs have produced an elevation of plasma lithium levels and a reduction in renal lithium clearance. The mean minimum lithium concentration increased 15% and the renal clearance was decreased by approximately 20%. These effects have been attributed to inhibition of renal prostaglandin synthesis by the NSAID. Thus, when NSAIDs and lithium are administered concurrently, subjects should be observed carefully for signs of lithium toxicity.
NSAIAs selective COX-2 inhibitors, prototypical NSAIAs may increase morbidity and mortality in patients with heart failure. Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Krill oil is POSSIBLY SAFE for most adults when used appropriately for a short amount of time up to three months. Research on krill oil has not adequately evaluated its safety or possible side effects. Sahib AS. Treatment of irritable bowel syndrome using a selected herbal combination of Iraqi folk medicines. KG GIVEN IN 2 DIVIDED DOSES. ONE-HALF OF THE 250 MG TABLET WILL BE NEEDED FOR DOSING LOWER-WEIGHT CHILDREN. DOSING WITH Naproxen Tablets IS NOT APPROPRIATE FOR CHILDREN WEIGHING LESS THAN 25 KILOGRAMS. Capone ML, Sciulli MG, Tacconelli S et al. Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects. J Am Coll Cardiol. Available as naproxen or naproxen sodium; each 220, 275, 412. Ann Ital Med Int. Discontinuing use of drugs called selective serotonin reuptake inhibitors SSRIs. Importance of discontinuing therapy and contacting clinician immediately if signs and symptoms of hepatotoxicity nausea, fatigue, lethargy, pruritus, jaundice, upper right quadrant tenderness, flu-like symptoms occur. Morrison BW, Daniels SE, Kotey P et al. Rofecoxib, a specific cyclooxygenase-2 inhibitor, in primary dysmenorrhea: a randomized controlled study. Obstet Gynecol. Before taking Colcrys, tell your doctor if you have liver or kidney disease, heart disease, a stomach ulcer, ulcerative colitis, Crohn's disease, intestinal bleeding, or any other severe gastrointestinal disorder. OTC preparations containing antihistamines, cough suppressants, expectorants, and nasal decongestants alone or in combination for relief of symptoms of upper respiratory tract infection. 265 266 Such preparations also may contain analgesics and antipyretics. 265 Limited evidence of efficacy for these preparations in this age group; appropriate dosages not established. Whether naproxen has a "steroid-sparing" effect has not been adequately studied. When added to the regimen of patients receiving gold salts, naproxen did result in greater improvement. Its use in combination with salicylates is not recommended because there is evidence that aspirin increases the rate of excretion of naproxen and data are inadequate to demonstrate that naproxen and aspirin produce greater improvement over that achieved with aspirin alone. In addition, as with other NSAIDs, the combination may result in higher frequency of adverse events than demonstrated for either product alone. Okonta JM, Uboh M, Obonga WO. Herb-Drug Interaction: A Case Study of Effect of Ginger on the Pharmacokinetic of Metronidazole in Rabbit.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Naprosyn, EC-Naprosyn, ANAPROX, ANAPROX DS and Naprosyn Suspension cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency. Abrupt discontinuation of corticosteroids may lead to disease exacerbation. Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue corticosteroids and the patient should be observed closely for any evidence of adverse effects, including adrenal insufficiency and exacerbation of symptoms of arthritis. In controlled clinical trials with about 80 pediatric patients and in well-monitored, open-label studies with about 400 pediatric patients with juvenile arthritis treated with naproxen, the incidence of rash and prolonged bleeding times were increased, the incidence of gastrointestinal and central nervous system reactions were about the same, and the incidence of other reactions were lower in pediatric patients than in adults. Nausea and vomiting following surgery. What is the normal function of the heart? Naproxen is a nonsteroidal anti-inflammatory drug NSAID with analgesic and antipyretic properties. The sodium salt of naproxen has been developed as a more rapidly absorbed formulation of naproxen for use as an analgesic. The mechanism of action of the naproxen anion, like that of other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition. Do NOT apply to open wounds or to skin that is broken, damaged, or irritated in any way. When used for self-medication, importance of reading the product labeling. Elevations of serum ALT or AST reported. See the end of this Medication Guide for a list of prescription NSAID medicines. Islam MS, Choi H. Comparative effects of dietary ginger Zingiber officinale and garlic Allium sativum investigated in a type 2 diabetes model of rats. J Med Food. Most minor burns will heal on their own, and home treatment is usually all that is needed to relieve your symptoms and promote healing. But if you suspect you may have a more severe injury, use first-aid measures while you arrange for an evaluation by your doctor. Microdiscectomy is done through a much smaller incision. Your surgeon inserts a thin tube with a camera on one end to see and remove the damaged disk. Gargle at least once each hour with 1 tsp 5 g of salt dissolved in 8 fl oz 240 mL of warm water.
Although Naprosyn, Naprosyn Suspension, EC-Naprosyn, ANAPROX and ANAPROX DS all circulate in the plasma as naproxen, they have pharmacokinetic differences that may affect onset of action. Onset of pain relief can begin within 30 minutes in patients taking naproxen sodium and within 1 hour in patients taking naproxen. Chadwick, L. R. In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders. Phytother. Swallow whole with liquid; do not split, chew, crush, or dissolve tablets. Long-term administration of NSAIDs has resulted in renal papillary necrosis and other renal injury. Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. In these patients, administration of a nonsteroidal anti-inflammatory drug may cause a dose-dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal decompensation. Patients at greatest risk of this reaction are those with impaired renal function, hypovolemia, heart failure, liver dysfunction, salt depletion, those taking diuretics and angiotensin converting enzyme ACE inhibitors or angiotensin receptor blockers ARBs and the elderly. Wang, N. Purification and characterization of trypsin-like enzymes from North Pacific krill Euphausia pacifica. Biotechnol. THAN 10-FOLD INCREASED RISK FOR DEVELOPING A GI BLEED COMPARED TO PATIENTS WITHOUT THESE RISK FACTORS. OTHER FACTORS THAT INCREASE THE RISK OF GI BLEEDING IN PATIENTS TREATED WITH NSAIDS INCLUDE LONGER DURATION OF NSAID THERAPY; CONCOMITANT USE OF ORAL CORTICOSTEROIDS, ASPIRIN, ANTICOAGULANTS, OR SELECTIVE SEROTONIN REUPTAKE INHIBITORS SSRIS; SMOKING; USE OF ALCOHOL; OLDER AGE; AND POOR GENERAL HEALTH STATUS. MOST POSTMARKETING REPORTS OF FATAL GI EVENTS OCCURRED IN ELDERLY OR DEBILITATED PATIENTS. Holtmann S, Clarke AH, Scherer H, et al. The anti-motion sickness mechanism of ginger. A comparative study with placebo and dimenhydrinate. Acta Otolaryngol. NSAIDs, including Naprosyn, EC-Naprosyn, ANAPROX, ANAPROX DS and Naprosyn Suspension, can lead to onset of new hypertension or worsening of pre-existing hypertension, either of which may contribute to the increased incidence of CV events. Patients taking thiazides or loop diuretics may have impaired response to these therapies when taking NSAIDs. NSAIDs, including Naprosyn, EC-Naprosyn, ANAPROX, ANAPROX DS and Naprosyn Suspension, should be used with caution in patients with hypertension. Blood pressure BP should be monitored closely during the initiation of NSAID treatment and throughout the course of therapy. Mixing alcohol and medicines puts you at risk for dangerous reactions. Chen, W. H. Gingerol inhibits cisplatin-induced vomiting by down regulating 5-hydroxytryptamine, dopamine and substance P expression in minks. Arch Pharm. Srivastava KC. Effect of onion and ginger consumption on platelet thromboxane production in humans. Safety of extended-release naproxen sodium tablets not established in children.
Importance of seeking immediate medical attention if signs and symptoms of a cardiovascular event chest pain, dyspnea, weakness, slurred speech occur. Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product. Your symptoms keep getting worse. Check with your pharmacist about how to dispose of unused medicine. Will my health care team communicate frequently with one another? Dose-dependent decreases in serum hemoglobin and hematocrit have been observed in patients treated with nonsteroidal anti-inflammatory drugs NSAIDs. Anemia has been reported occasionally. The mechanism may involve NSAID-induced fluid retention or gastrointestinal blood loss, or an incompletely described effect on erythropoiesis. What is naproxen Naprosyn, Anaprox, Anaprox DS? The AV node serves as an relay station between the atria and the ventricles. Signals from the atria must pass through the AV node to reach the ventricles. FDA pregnancy category C. Before using naproxen, tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking naproxen during the last 3 months of pregnancy may result in birth defects. Niempoog S, Siriarchavatana P, Kajsongkram T. The efficacy of Plygersic gel for use in the treatment of osteoarthritis of the knee. Some people pour the fresh juice on their to treat burns. The oil made from ginger is sometimes applied to the skin to relieve pain. COLLABORATION META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS DEMONSTRATED AN APPROXIMATELY TWO-FOLD INCREASE IN HOSPITALIZATION FOR HEART FAILURE IN COX-2 SELECTIVE-TREATED PATIENTS AND NONSELECTIVE NSAID-TREATED PATIENTS COMPARED TO PLACEBO-TREATED PATIENTS. IN A DANISH NATIONAL REGISTRY STUDY OF PATIENTS WITH HEART FAILURE, NSAID USE INCREASED THE RISK OF MI, HOSPITALIZATION FOR HEART FAILURE, AND DEATH. ADDITIONALLY, FLUID RETENTION AND EDEMA HAVE BEEN OBSERVED IN SOME PATIENTS TREATED WITH NSAIDS.
Do not take more than 4000 milligrams of acetaminophen per day. RENAL FUNCTION, HYPOVOLEMIA, HEART FAILURE, LIVER DYSFUNCTION, SALT DEPLETION, THOSE TAKING DIURETICS AND ACE INHIBITORS OR ARBS, AND THE ELDERLY. DISCONTINUATION OF NSAID THERAPY IS USUALLY FOLLOWED BY RECOVERY TO THE PRETREATMENT STATE. NO INFORMATION IS AVAILABLE FROM CONTROLLED CLINICAL STUDIES REGARDING THE USE OF NAPROXEN IN PATIENTS WITH ADVANCED RENAL DISEASE. THE RENAL EFFECTS OF NAPROXEN MAY HASTEN THE PROGRESSION OF RENAL DYSFUNCTION IN PATIENTS WITH PREEXISTING RENAL DISEASE. Jatsa, H. B. Evaluation of androgenic activity of Zingiber officinale and Pentadiplandra brazzeana in male rats. Focardi, S. Polybrominated diphenyl ethers, polychlorinated dibenzo-dioxins, -furans, and -biphenyls in three species of Antarctic penguins. Environ Sci Pollut. Do not use this medicine without a doctor's advice if you are pregnant. There is some evidence to suggest that when inhibitors of prostaglandin synthesis are used to delay preterm labor there is an increased risk of neonatal complications such as necrotizing enterocolitis, patent ductus arteriosus and intracranial hemorrhage. Naproxen treatment given in late pregnancy to delay parturition has been associated with persistent pulmonary hypertension, renal dysfunction and abnormal prostaglandin E levels in preterm infants. Because of the known effects of nonsteroidal anti-inflammatory drugs on the fetal cardiovascular system closure of ductus arteriosus use during pregnancy particularly late pregnancy should be avoided. Take it easy for a few days. Rest can relieve swelling and give your back time to heal. While your back hurts, avoid and other activities where you have to bend or lift. Mozaffari-Khosravi H, Talaei B, Jalali BA, Najarzadeh A, Mozayan MR. The effect of ginger powder supplementation on insulin resistance and glycemic indices in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial. Nieman DC, Shanely RA, Luo B, Dew D, Meaney MP, Sha W. A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial. For cramping from diarrhea, medicines that have loperamide Imodium or bismuth subsalicylate Kaopectate or Pepto-Bismol might make you feel better. Ask your health care provider any questions you may have about how to use Naprosyn.
Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Naproxen pharmacokinetics has not been determined in subjects with renal insufficiency. Given that naproxen, its metabolites and conjugates are primarily excreted by the kidney, the potential exists for naproxen metabolites to accumulate in the presence of renal insufficiency. Elimination of naproxen is decreased in patients with severe renal impairment. Adjust dosage based on individual requirements and response; attempt to titrate to the lowest effective dosage. Please refer to the for information on shortages of one or more of these preparations. What are rheumatoid arthritis causes and risk factors? Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb1-induced teratogenicity using a whole rat embryo culture model. Concomitant administration of delayed-release naproxen tablets with drugs that increase gastric pH not recommended; possible pharmacokinetic interaction.
Warnings: Pregnancy and breast-feeding: Jiaogulan is POSSIBLY UNSAFE when taken by mouth during pregnancy. One of the chemicals in jiaogulan has been linked to possible birth defects. Not enough is known about the safety of jiaogulan during breast-feeding. Stay on the safe side and avoid use. “Auto-immune diseases” such as multiple sclerosis MS lupus systemic lupus erythematosus, SLE rheumatoid arthritis RA or other conditions: Jiaogulan might cause the immune system to become more active. This could increase the symptoms of auto-immune diseases. Of the material excreted in the urine, 32% is conjugated. You also can do things to make stomach pain less likely. Codeine is secreted into human milk. In women with normal codeine metabolism normal CYP2D6 activity the amount of codeine secreted into human milk is low and dose-dependent. Despite the common use of codeine products to manage postpartum pain, reports of adverse events in infants are rare. However, some women are ultra-rapid metabolizers of codeine. These women achieve higher-than-expected serum levels of codeine's active metabolite, morphine, leading to higher-than-expected levels of morphine in breast milk and potentially dangerously high serum morphine levels in their breastfed infants. Therefore, maternal use of codeine can potentially lead to serious adverse reactions, including death, in nursing infants. Your local hospital. Ask your local hospital or medical center if they have or are affiliated with a pain treatment center. If the hospital does not have one, ask to speak with their department of anesthesiology, which may have doctors on staff who can refer you to a different hospital. Micklefield GH, Redeker Y, Meister V, et al. Effects of ginger on gastroduodenal motility. Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Elimination of acetaminophen is principally by liver metabolism conjugation and subsequent renal excretion of metabolites. Approximately 85% of an oral dose appears in the urine within 24 hours of administration, most as the glucuronide conjugate, with small amounts of other conjugates and unchanged drug. Ginger might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking ginger along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed. Usually administered orally twice daily. 225 When used for the management of osteoarthritis, rheumatoid arthritis, or ankylosing spondylitis, the morning and evening doses may be unequal in size.
Pascoe, J. E. Variation in concentration and labeling of ginger root dietary supplements. Obstet. One or 2 capsules every 4 hours. Total daily dosage should not exceed 6 capsules. Akhani SP, Vishwakarma SL, Goyal RK. Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats. Elevation. Elevate the injured or sore area on pillows while applying ice and anytime you are sitting or lying down. Try to keep the area at or above the level of your to help minimize swelling. Food and Drug Administration. Cough and cold medications in children less than two years of age. Rockville, MD; 2007 Jan 12. From FDA website.
In patients taking NSAIDs, the following adverse experiences have also been reported in approximately 1% to 10% of patients. Ginger is a plant with leafy stems and yellowish green flowers. The ginger spice comes from the roots of the plant. Ginger is native to warmer parts of Asia, such as China, Japan, and India, but now is grown in parts of South American and Africa. It is also now grown in the Middle East to use as medicine and with food. Leach MJ, Kumar S. The clinical effectiveness of ginger Zingiber officinale in adults with osteoarthritis. Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Hsu, S. L. Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells. Chopra A, Saluja M, Tillu G, Sarmukkaddam S, Venugopalan A, Narsimulu G, Handa R, Sumantran V, Raut A, Bichile L, Joshi K, Patwardhan B. Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial. Constipation; diarrhea; dizziness; drowsiness; gas; heartburn; nausea; stomach upset; vomiting. Medicines to help ease cold and are formulated differently for children and adults. You should never give an adult cold medicine to a child, not even in a smaller amount. And you should always call your doctor if your develops a cold or a fever. For morning sickness: 500 to 2500 mg of ginger daily in two to four divided doses for 3 days to 3 weeks has been used.
Govindarajan, M. The essential oil of Zingiber officinalis Linn Zingiberaceae as a mosquito larvicidal and repellent agent against the filarial vector Culex quinquefasciatus Say Diptera: Culicidae. Parasitol. Some naproxen side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Avoid drinking alcohol. It may increase your risk of stomach bleeding. Select the bandage carefully. There are many products available. Liquid skin bandages and moisture-enhancing bandages are available with other products. Before you buy or use one, be sure to read the label carefully, and follow the label's instructions when you apply the bandage. CFR Part 201. Final rule. GlaxoSmithKline. Treximet sumatriptan succinate and naproxen sodium tablets prescribing information. Research Triangle Park, NC; 2012 Oct. Kvien TK, Hoyeraal HM, Sandstad B. Naproxen and acetylsalicylic acid in the treatment of pauciarticular and polyarticular juvenile rheumatoid arthritis: assessment of tolerance and efficacy in a single-centre 24-week double-blind parallel study. Scand J Rheumatol. Sambaiah, K. and Srinivasan, K. Effect of cumin, cinnamon, ginger, mustard and tamarind in induced hypercholesterolemic rats. If you have a sun allergy, the outlook is usually very good, especially if you consistently use sunscreens and protective clothing. Most people with PMLE or actinic prurigo improve significantly within five to seven years after diagnosis, and almost everyone with photoallergic eruption can be cured by avoiding the specific chemical that triggers the sun allergy. PACKAGED IN LIGHT-RESISTANT BOTTLES OF 100 AND 1000. Brenner, D. E. Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjects. Cancer Epidemiol. How Are Neck and Shoulder Pain Treated? Heat burns thermal burns: Smother any flames by covering them with a blanket or water. If your clothing catches fire, do not run: stop, drop, and roll on the ground to smother the flames.
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AVOID ADMINISTRATION OF MORE THAN ONE NSAID AT A TIME. Chou R, Helfand M, Peterson K et al. Comparative effectiveness and safety of analgesics for osteoarthritis. Comparative effectiveness review no. 4. Prepared by the Oregon evidence-based practice center under contract no. 290-02-0024. Reubsaet, L. Elucidation of phosphatidylcholine composition in krill oil extracted from Euphausia superba. You may need to take a second lower dose of Colcrys 1 hour after the first dose if you still have gout pain. Follow your doctor's instructions. Early symptoms following a potentially hepatotoxic overdose may include: nausea, vomiting, diaphoresis, and general malaise. Clinical and laboratory evidence of hepatic toxicity may not be apparent until 48 to 72 hours post-ingestion.
Naprosyn is to be used only by the patient for whom it is prescribed. Do not share it with other people. Gawad, H. S. Modulating effect of ginger extract on rats with ulcerative colitis. J Ethnopharmacol. Visual disturbances reported; ophthalmic evaluation recommended if visual changes occur. Self-medication should not exceed 3 days. NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms.
What happens if I overdose? Syntex regarding labeling revisions about gastrointestinal adverse reactions to Naprosyn and Anaprox naproxen sodium. Rockville, MD: Food and Drug Administration, Division of Oncology and Radiopharmaceutical Drug Products; 1988 Sep. Houghton, P. J. Cardiovascular effects of ginger aqueous extract and its phenolic constituents are mediated through multiple pathways. Vascul.
You might try a heating pad to ease belly pain. Chamomile or peppermint tea may help with gas. Be sure to drink plenty of clear fluids so your body has enough water. Kidd, P. M. Krill oil complex: potent nutraceutical synergy. What new information about RA has come from the 2015 national meeting of the American College of Rheumatology?